The mission of Science Resources Foundation is to ensure healthy and sustainable communities. Our current projects are listed below

Global Health: AI approaches in precision medicine using in silico metabolic models of pathogens

Bannerman BP, Oarga A, Júlvez J, Mycobacterial metabolic model development for drug target identification, Gigabyte, April, 2023 https://doi.org/10.46471/gigabyte.80

Bannerman BP, Vedithi, S, Julvez J, Munir A, Skwark M, Oliver S and Blundell, TL. Comparative pathway analysis of mycobacterial species provides insight into the identification of new drug targets, 2019. doi: https://doi.org/10.1101/535856.

Jackson, A. P., Sanders, M., Berry, A., McQuillan, J., Aslett, M. A., Quail, M. A., Bannerman-Chukualim, B. P. et al. (2010) The genome sequence of Trypanosoma brucei gambiense, Causative agent of chronic Human African Trypanosomiasis. PLoS Negl. Trop. Dis. 4(4):

Bannerman-Chukualim, B., Peters, N., Fowler, C. H. and Berriman, M. (2008). TrypanoCyc – a metabolic pathway database for Trypanosoma brucei. BMC Bioinformatics. 9(10): 1–2.

Shameer, S., Logan-Klumpler, F.J., Vinson, F., Cottret, L., Merlet, B., Achcar, F., Boshart, M., Berriman, M., Breitling, R., Bringaud, F., Bütikofer, P., Cattanach, A. M., Bannerman-Chukualim, B. P. et al. (2014) TrypanoCyc: a community-led biochemical pathways database for Trypanosoma brucei. Nucleic Acids Res. 43: D637–D644.

Global Health: Treatment management insights through Host-Pathogen interactions

Bannerman, B. P, Jorge Júlvez, Alexandru Oarga, Tom L Blundell, Pablo Moreno, and R Andres Floto. 'Integrated Human/SARS-CoV-2 Metabolic Models Present Novel Treatment Strategies against COVID-19'. Life Science Alliance 4, no. 10 (1 October 2021): e202000954. https://doi.org/10.26508/lsa.202000954.

Beaudoin CA, Jamasb AR, Alsulami AF, Copoiu L, van Tonder AJ, Hala S, Bannerman BP, Thomas SE, Vedithi SC, Torres PHM, Blundell TL. Predicted structural mimicry of spike receptor-binding motifs from highly pathogenic human coronaviruses. https://www.sciencedirect.com/science/article/pii/S2001037021002798

Alsulami AF, Thomas SE, Jamasb AR, Beaudoin CA, Moghul I, Bannerman BP, Copoiu L, Vedithi SC, Torres P, Blundell TL. SARS-CoV-2 3D database: understanding the coronavirus proteome and evaluating possible drug targets. Brief Bioinform. 2021 Mar 22;22(2):769-780. doi: 10.1093/bib/bbaa404. PMID: 33416848; PMCID: PMC7929435.

Bannerman B, Kramer S, Dorrell R, and Carrington M. Multispecies reconstructions uncover widespread conservation, and lineage-specific elaborations in eukaryotic mRNA metabolism, 2018. PLOS ONE 13(3): e0192633.

Sponsors: Schlumberger Foundation Faculty for the Future, Wellcome Trust, MRC, WHOTDR, Spanish Ministry of Science and Technology]

Capacity Building

The Science Resources Foundation has an established capacity building programme through the Science Resources Africa initiative (https://www.scienceresourcesafrica.com/)